STAT Plus: Momenta Pharma drug improves symptoms in patients with myasthenia gravis

Momenta Pharmaceuticals reported Monday that in a mid-stage clinical trial, an experimental medicine significantly improved the symptoms of patients with generalized myasthenia gravis, a rare neuromuscular disease.

Called nipocalimab, the Momenta drug works by blocking a molecule in the body called neonatal Fc receptor (FcRn), which can trigger certain types of autoimmune diseases. Generalized myasthenia gravis is a chronic and debilitating condition in which the body’s own antibodies disrupt the communication between nerve endings and muscles.

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